To prevent hard-to-remove stains from appearing on your IceFiber™ Hugging pillowcases, clean them as soon as they appear: - Step 1: Dry the stains with a damp cloth - Step 2: Remove the pillowcase IceFiber™ for washing (depending on how dirty the case is) - Step 3: Mix diluted vinegar (½ vinegar, ½ water), or mix with baking soda and use a spray bottle to spray the stain, use a cloth Blot dry as in step 1. - Step 4: Repeat until stains are cleaned. In addition, you should regularly clean the IceFiber™ pillowcase to keep the pillowcase clean from dirt and dead cells during use.